PLASMA THERAPY - SCIENCE AND TECHNOLOGY

News: No antibiotics, plasma therapy to treat adult COVID patients: government

 

What's in the news?

       The COVID-19 National Task Force of the Ministry of Health and Family Welfare issued revised clinical guidelines for the management of adult COVID-19 patients.

       As per the new guidelines, convalescent plasma therapy and drugs, including lopinavir-ritonavir, molnupiravir, favipiravir, azithromycin and doxycycline, are not to be used for treatment.

 

Key takeaways:

       Antibiotics should not be used unless there is clinical suspicion of bacterial infection. The possibility of co-infection of COVID-19 with other endemic infections must be considered.

       Physical distancing, indoor mask use, hand hygiene, symptomatic management (hydration, anti-pyretics, antitussive), monitoring temperature and oxygen saturation (with pulse oximeters) is vital.

       Patients are advised to seek immediate medical attention if there is difficulty breathing, high-grade fever/ severe cough, particularly if lasting for more than five days.

 

Plasma Therapy:

       Plasma is the liquid part of the blood. Convalescent plasma, extracted from the blood of patients recovering from an infection, is a source of antibodies against the infection.

       The therapy involves using their plasma to help others recover.

       For Covid-19, this has been one of the treatment options.

       A COVID-19 patient usually develops primary immunity against the virus in 10-14 days.

       The donor would have to be a documented case of Covid-19 and healthy for 28 days since the last symptoms.

 

Why was Plasma Therapy discontinued?

       An ICMR study has found convalescent plasma was not associated with a reduction in progression to severe Covid-19 or all-cause mortality.