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OBELISKS – SCI & TECH

Published 28 Feb 2024. Access the PDF directly or read the stored explanation below.

UPSC English 28 Feb 2024

OBELISKS – SCI & TECH

News: A New Obelisk ‘Lifeform’ Is Hiding Inside Humans

 

What's in the news?

●       Stanford University researchers have discovered virus-like ‘lifeforms’ that exist inside human mouths and guts.

●       Smaller than a virus and not considered standard life, the genetic material can still transfer information that can be read by a cell.

 

Obelisks:

●       It is a newly discovered class of virus-like entities present in the human body.

●       It comprises a class of diverse RNAs that have colonized and gone unnoticed in human and global microbiomes.

●       Named after the highly symmetrical, rod-like structures formed by their twisted lengths of RNA, the Obelisks' genetic sequences are only around 1,000 characters (nucleotides) in size.

 

Features:

●       These mysterious bits of genetic material have no detectable sequences or even structural similarities known to any other biological agents.

●       They're also significantly larger than other genetic molecules that coexist inside cells, from plants to bacteria, called plasmids, which are more commonly composed of DNA.

●       Obelisks represent their own class of organism. They lie somewhere between viruses and viroids.

●       Although the hosts of other obelisks remain unknown, there is a possibility that some of them may be found in bacteria.

●       Different types of Obelisks appear to be present in different areas of our bodies.

 

Go back to basics:

Viroids:

●       Viroids are tiny loops of RNA, a genetic cousin of DNA and they've been found to infect primarily plants.

 

Difference Between Viroids and RNA Viruses:

Viroids differ from larger, RNA-based viruses in several ways.

●       Viriods are naked, lacking the protective shells that viruses use to hold their genetic material.

●       The RNA of Viriods doesn't contain instructions to build proteins; whereas viruses carry instructions for their outer shells and for certain enzymes they need to replicate, viroids co-opt these enzymes from their hosts.

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